From a clinician’s point of view, the principal limitation of the current methods
of acute mountain sickness (AMS) assessment is reliance on self-reporting of AMS symptoms,
which can be heavily influenced by multiple factors, including psychological factors.
1
Objective measurement of maladaptation to hypobaric hypoxia at high altitude would
be clearly preferred. Heart rate and oxygen saturation values, albeit measured on
most expeditions, are not diagnostic criteria for AMS. Their usability to detect or
predict the occurrence of AMS by nonmedical personnel is, at best, limited. High-altitude
medicine is still searching for a reliable, objective way to assess AMS that is easy
to use even without medical training, inexpensive, and lightweight.To read this article in full you will need to make a payment
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References
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- Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α.Aging (Albany NY). 2020; 12: 10931-10950
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Article info
Publication history
Published online: January 05, 2023
Publication stage
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© 2022 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
