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Original research| Volume 21, ISSUE 4, P298-302, December 2010

Accuracy of Internet Recommendations for Prehospital Care of Venomous Snake Bites

      Objective

      To evaluate the accuracy of Internet information regarding the prehospital care of venomous snake bites.

      Methods

      Two major search engines were used to identify 48 Web sites regarding 6 prehospital treatment options for snake bite (removal of constrictive devices, ice, heat, electric shock, incision, and suction). Web sites were evaluated for their quality using the Health on the Net (HON) seal and Journal of the American Medical Association (JAMA) benchmarks.

      Results

      Of the 48 Web sites reviewed, 26 (54.1%) contained inappropriate recommendations. The remaining 22 Web sites were appropriate regarding all modalities addressed. Among the Web sites reviewed, inappropriate treatment recommendations included: suction (14); ice (6); incision (4); electric shock (1). Five Web sites that met all 4 JAMA benchmarks and the HON seal included 3 inappropriate treatment recommendations. Conversely, the 5 Web sites that met none of the JAMA benchmarks nor included the HON seal included only 2 inappropriate treatment measures.

      Conclusion

      This study highlights the variety of misinformation available on the Internet regarding prehospital care of snake bites, and the unreliability of the HON seal and JAMA benchmarks as markers of accuracy. As the Internet becomes an increasing source of medical information for both the public and clinicians, the importance of accurate Web sites becomes imperative. Clinicians and lay people should be aware of the high variability of Internet information regarding snake bite prehospital care.

      Key Words

      Introduction

      Venomous snakes exist on all 7 continents except Antarctica.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      North Americans suffer approximately 45 000 snake bites each year with about 8000 bites from venomous species.
      • Gold B.S.
      • Barish R.A.
      • Dart R.C.
      North American snake envenomation: diagnosis, treatment and management.
      In the past, a variety of prehospital modalities primarily based on customary practice or folklore rather than sound scientific data were advocated to prevent the spread of venom. These practices include incising the bite site, applying suction to the wound, and administering electrical shocks.
      • Bush S.P.
      Snake suction devices don't remove venom: they just suck.
      Research has demonstrated that the majority of these prehospital treatments are ineffective, and many may be potentially harmful.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Bush S.P.
      Snake suction devices don't remove venom: they just suck.
      In 2007 Boyd et al published an article in Wilderness and Environmental Medicine reviewing the current literature on first aid care for snake bite.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      This article's recommendations for prehospital care of snake bites were consistent with those of the American Red Cross and American Heart Association (ARC/AHA) recommendations for first aid.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      2005 American Heart Association guidelines for cardiopulmonary resuscitationemergency cardiovascular care Part 14: First aid.
      Boyd et al also reported that increased harm can result from ice, incision, suction, heat, or electrical shock.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      2005 American Heart Association guidelines for cardiopulmonary resuscitationemergency cardiovascular care Part 14: First aid.
      Previous studies reviewing the Internet for medical information regarding other topics, such as infertility, head and neck cancer, and methotrexate treatment, have reported high variability in the accuracy of available information.
      • Ni Riordain R.
      • McCreary C.
      Head and neck cancer information on the Internet: Type, accuracy and content.
      • Thompson A.E.
      • Graydon S.L.
      Patient-oriented methotrexate information sites on the Internet: a review of completeness, accuracy, format, reliability, credibility, and readability.
      • Marriott J.V.
      • Stec P.
      • El-Toukhy T.
      • et al.
      Infertility information on the World Wide Web: a cross-sectional survey of quality of infertility information on the Internet in the UK.
      These studies are alarming due to the high use of the Internet by the public. For example, a poll in 2001 demonstrated almost 100 million adults regularly use the Internet to gain medical information.
      • Wilson P.
      How to find the good and avoid the bad or ugly: a short guide to tools for rating quality of health information on the Internet.
      However, this situation does not pertain solely to the general public. Sigouin and Jadad reported that 64% of family physicians, 72% of nurses, and 100% of the oncologists in the study used the Internet for medical advice.
      • Sigouin C.
      • Jadad A.
      Awareness of sources of peer-reviewed research evidence on the Internet.
      Since both the general public and health care professionals are utilizing the Internet for advice on patient care, we sought to review this advice and compare it to current guidelines regarding the appropriate prehospital management of snake bite.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Bush S.P.
      Snake suction devices don't remove venom: they just suck.

      Methods

      An Internet search for both “snake bite treatment” and “snake bite first aid” was completed using the 2 search engines www.google.com and www.yahoo.com. With each search topic and search engine, the initial 25 Web sites were reviewed based on their content generating a total of 100 Web sites available for screening. This design was based on previous published research pertaining to Internet data.
      • Ni Riordain R.
      • McCreary C.
      Head and neck cancer information on the Internet: Type, accuracy and content.
      • Thompson A.E.
      • Graydon S.L.
      Patient-oriented methotrexate information sites on the Internet: a review of completeness, accuracy, format, reliability, credibility, and readability.
      • Marriott J.V.
      • Stec P.
      • El-Toukhy T.
      • et al.
      Infertility information on the World Wide Web: a cross-sectional survey of quality of infertility information on the Internet in the UK.
      Web sites not addressing snakebite care for humans, duplicate Web sites, and commercial Web sites were not included in the review narrowing the field to 48 Web sites for evaluation.
      The content of all remaining 48 sites was assessed for each of the following 6 treatment modalities: removal of constrictive items, ice, heat, electrical shock, incision, and suction. Support “for the modality,” “against the modality,” or “not addressed” was documented for each site regarding each treatment modality and compared with recommendations regarding the appropriateness of the treatment as described by Boyd et al
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      (Table 1).
      Table 1Prehospital snakebite management appropriate and inappropriate therapies
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      Appropriate treatmentsInappropriate treatments
      Removal of constrictive itemsIncision
      Pressure immobilizationSuction
      Basic life supportHeat
      Pain controlIce
      HydrationAlcohol
      Electric shock
      Topical chemicals/herbals
      Removal of constrictive items (beneficial). Any items such as watches, rings, or clothing near the bite should be removed to prevent a tourniquetlike effect.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      This tourniquetlike effect can worsen local tissue damage via vascular compromise.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Kunkel D.
      Bites of venomous reptiles.
      Ice (not beneficial). Traditionally, ice was recommended for its theoretical benefit of decreasing humeral response and enzyme activity.
      • Stahnke H.
      The L-C treatment of venomous bites or stings.
      • Stahnke H.
      • Allen F.
      • Horan R.
      • et al.
      The treatment of snake bite.
      However, further evaluation revealed that ice actually worsens the severity of tissue damage.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Cohen W.
      • Wetzel W.
      • Kadish A.
      Local heat and cold application after eastern cottonmouth moccasin (Agkistrodon piscivorus) envenomation in the rat: effect on tissue injury.
      • Ya P.M.
      • Perry Jr, J.F.
      Experimental evaluation of methods for the early treatment of snake bite.
      Heat (not beneficial). Heat was originally theorized to increase local blood flow with the intent to disseminate venom and decrease local tissue necrosis.
      • Cohen W.
      • Wetzel W.
      • Kadish A.
      Local heat and cold application after eastern cottonmouth moccasin (Agkistrodon piscivorus) envenomation in the rat: effect on tissue injury.
      • Ya P.M.
      • Perry Jr, J.F.
      Experimental evaluation of methods for the early treatment of snake bite.
      Animal models failed to demonstrate any efficacy of this modality and found that heat potentially worsens local tissue damage.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Cohen W.
      • Wetzel W.
      • Kadish A.
      Local heat and cold application after eastern cottonmouth moccasin (Agkistrodon piscivorus) envenomation in the rat: effect on tissue injury.
      • Ya P.M.
      • Perry Jr, J.F.
      Experimental evaluation of methods for the early treatment of snake bite.
      Electrical shock (not beneficial). The concept of electrical shock originated in 1986 from the jungles of the Amazon.
      • Guderian R.
      • Mackenzie C.
      • Williams J.
      High voltage shock treatment for snake bite (letter).
      Since 1986, basic science has been unable to demonstrate an effective pathophysiological mechanism for care of snake bite via electric shock.
      • Howe N.R.
      Electric shock does not save snakebitten rats.
      • Johnson E.K.
      • Kardong K.V.
      • Mackessy S.P.
      Electric shocks are ineffective in treatment of lethal effects of rattlesnake envenomation in mice.
      • Snyder C.
      • Murdock R.
      • White G.
      • et al.
      Electric shock treatment for snakebite (letter).
      • Stoud C.
      • Amon H.
      • Wagnor T.
      • Falk J.L.
      Effect of electric shock therapy on local tissue reaction to poisonous snake venom injection in rabbits.
      Additionally, case reports have demonstrated the danger of electrical shock therapy for snakebites.
      • Dart R.
      • Gustafson R.
      Failure of electric shock treatment for rattlesnake envenomation.
      • Russell F.
      A letter on electroshock for snakebite.
      Incision (not beneficial). Incision combined with suction was once considered the standard of care.
      • Alberts M.B.
      • Shalit M.
      • LoGalbo F.
      Suction for venomous snakebite; a study of “mock venom” extraction in a human model.
      Incision, now, is felt to place the patient at greater risk than potential benefit. Incision can damage underlying structures, introduce infection, and create significant bleeding.
      • Alberts M.B.
      • Shalit M.
      • LoGalbo F.
      Suction for venomous snakebite; a study of “mock venom” extraction in a human model.
      Suction (not beneficial). Initially intended to remove venom from the wound site, suction devices have been demonstrated to create local tissue injury without significant venom extraction.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Bush S.P.
      Snake suction devices don't remove venom: they just suck.
      2005 American Heart Association guidelines for cardiopulmonary resuscitationemergency cardiovascular care Part 14: First aid.
      • Alberts M.B.
      • Shalit M.
      • LoGalbo F.
      Suction for venomous snakebite; a study of “mock venom” extraction in a human model.
      Suction devices also impair the natural wound healing process.
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      • Bush S.P.
      Snake suction devices don't remove venom: they just suck.
      • Alberts M.B.
      • Shalit M.
      • LoGalbo F.
      Suction for venomous snakebite; a study of “mock venom” extraction in a human model.
      Each Web site was also assessed for the 4 Journal of the American Medical Association (JAMA) publishing benchmarks: authorship, references, date of last update, and disclosure of conflict of interest. Based on this system, sites meeting 3 or more JAMA benchmarks were viewed as higher-quality Web sites, and those meeting 2 or less JAMA Benchmarks were viewed as lower-quality Web sites.
      • Meric F.
      • Bernstam E.
      • Mirza N.
      • et al.
      Breast cancer on the World Wide Web: cross sectional survey of quality of information and popularity of websites.
      In addition, each Web site was evaluated for the Health on the Net Seal (HON). This nonprofit organization reviews health information Web sites with an 8-point code of conduct (Table 2) that must be met to display the Health on the Net Seal.
      • Meric F.
      • Bernstam E.
      • Mirza N.
      • et al.
      Breast cancer on the World Wide Web: cross sectional survey of quality of information and popularity of websites.
      This distinction has been suggested to be the oldest and most well-known quality label of Internet health information.
      • Meric F.
      • Bernstam E.
      • Mirza N.
      • et al.
      Breast cancer on the World Wide Web: cross sectional survey of quality of information and popularity of websites.
      Table 2Health on the Net Code http://www.hon.ch/HONcode/Pro/Conduct.html
      1. Authoritative—indicate the qualification of the authors
      2. Complementarity—information should support, not replace, the doctor patient relationship
      3. Privacy—respect the privacy and confidentiality of personal data submitted to the site by the visitor
      4. Attribution—cite the source(s) of published information, date and medical and health pages
      5. Justifiability—site must back up claims relating to benefits and performance
      6. Transparency—accessible presentation, accurate e-mail contact
      7. Financial disclosure—identify funding resources
      8. Advertising policy—clearly distinguish advertising from editorial content

      Results

      Forty-eight Web sites were reviewed for their recommendations regarding 6 potential treatment options for a venomous snake bite. All sites addressing the modalities of heat and removal of constrictive items were in agreement with current evidence-based literature recommendations by Boyd et al and ARC/AHA for snakebite first aid regarding these issues (Table 1).
      • Boyd J.J.
      • Agazzi G.
      • Svajda D.
      • et al.
      Venomous snakebite in mountainous terrain: prevention and management.
      2005 American Heart Association guidelines for cardiopulmonary resuscitationemergency cardiovascular care Part 14: First aid.
      Multiple Web sites, however, recommend other inappropriate therapies regarding snakebite prehospital care: 6 recommended use of ice, 4 recommended incision, 14 recommended use of suction, and 1 recommended electric shock (Figure).
      Figure thumbnail gr1
      FigureWeb site recommendations for snake bite first aid.
      Overall, 22 Web sites were correct in all treatment modalities addressed. No Web site supported greater than 4 improper treatment modalities. Four Web sites recommended 2 to 4 inapropriate prehospital treatments (Table 3).
      Table 3Number of Web sites with corresponding number of inaccuracies
      Number of inaccuraciesNumber of Web sites
      022
      122
      21
      32
      41
      50
      60
      70
      Web sites were evaluated by the number of JAMA benchmarks they met combined with display of Health on the Net Seal (HON seal). Five Web sites met all 4 JAMA benchmarks and included the HON seal. Of these 5 Web sites, 3 recommended use of suction. Five Web sites met none of the JAMA benchmarks nor included the HON seal. Of these 5 Web sites, 2 recommended use of suction. The majority of the Web sites met 3 out of 5 measures with regards to the JAMA benchmarks and the HON seal (Table 4).
      Table 4Correlation of inaccuracies and Web site quality
      Web site quality
      Web site quality is defined as the number of Journal of the American Medical Association (JAMA) publishing benchmarks met by each website plus the presence of a Health on the Net (HON) certification seal. Category 5 indicates the highest quality (all 4 JAMA benchmarks met plus a HON seal).
      N (%) Web sitesTotal # of inaccuracies
      05 (10.40%)2
      19 (18.80%)7
      211 (22.90%)9
      315 (31.30%)12
      43 (6.30%)1
      55 (10.40%)3
      Total48 (100%)34
      a Web site quality is defined as the number of Journal of the American Medical Association (JAMA) publishing benchmarks met by each website plus the presence of a Health on the Net (HON) certification seal. Category 5 indicates the highest quality (all 4 JAMA benchmarks met plus a HON seal).

      Discussion

      More than half of the Internet sites reviewed contained inappropriate information regarding the prehospital treatment of venomous snake bite, making the chances of being exposed to correct treatment information essentially equal to a coin toss. Of further concern was the fact that no correlation was observed between the accuracy of the information presented and the quality of the Web site as assessed by 2 accepted medical Internet quality seals.
      With approximately 8000 bites from venomous snakes per year in the United States, it is critical that patients receive appropriate prehospital care.
      • Gold B.S.
      • Barish R.A.
      • Dart R.C.
      North American snake envenomation: diagnosis, treatment and management.
      A key to appropriate care is proper education/knowledge. As demonstrated in previous research, both clinicians and patients have become reliant upon the Internet for components of their knowledge and education.
      • Wilson P.
      How to find the good and avoid the bad or ugly: a short guide to tools for rating quality of health information on the Internet.
      This study unfortunately highlights the variety of misinformation available on the Internet regarding prehospital care of snake bite.
      With increasing reliance upon the Internet for information, entities such as JAMA and the nonprofit organization Health on the Net have attempted to develop standards for evaluating Web sites for their quality. In this study, inaccuracies still plagued sites that met high-quality standards by both JAMA and the HON seal. Inability to rely on these screening tools for Internet education regarding snake bite prehospital care adds complexity to Internet education for both clinicians and patients.
      The data search in this study included MedlinePlus.gov, an Internet Web site created in 2004 by the American College of Physicians and the National Library of Medicine to provide patients with reliable unbiased health information.
      • Smalligan R.D.
      • Campbell E.O.
      • Ismaill H.M.
      Patient experiences with MedlinePlus.gov: a survey of internal medicine patients.
      This traditionally respected source is often relied upon to contain the most up-to-date information when addressing medical topics such as snake bite prehospital care. However, this site supported the use of suction. Two other reputable sources of Internet information, the Food and Drug Administration (fda.gov) and the University of Maryland Medical Center (umm.edu), also contained non-evidence-based recommendations for use of suction in snakebite prehospital care.
      As the available data regarding prehospital care of snake bites have increased, sound scientific practices have replaced traditional remedies in snakebite treatment. Many people use the Internet as a source of medical information and with increasing availability of wireless Internet in the prehospital areas; the importance of accurate Web sites for both clinician and lay person education becomes imperative. Use of government and academic Web sites and/or screening tools such as the HON seal and JAMA benchmarks in theory provides clinicians and lay persons with more accurate data regarding medical care. However, lay people and clinicians should be aware that, as demonstrated in this study, these Web sites may not contain accurate medical information.

      Limitations

      There are limitations to our findings. Web site quality was measured by only 1 individual evaluating each Web site. If the same data were acquired by another individual, the data could be subjected to some interobserver analysis to assess the reliability (precision) of the measurement. Additionally, only the first 25 “hits” of 2 major United States search engines were utilized, which limits the generalizability of these results to all Web sites. The external validity of the data could be enhanced if international search engines were also evaluated. Not all modalities of treatment of snake bites (eg, safety, communications, and transport) were evaluated within this study, which could further vary the accuracy of the Web sites.

      References

        • Boyd J.J.
        • Agazzi G.
        • Svajda D.
        • et al.
        Venomous snakebite in mountainous terrain: prevention and management.
        Wilderness Environ Med. 2007; 18: 190-202
        • Gold B.S.
        • Barish R.A.
        • Dart R.C.
        North American snake envenomation: diagnosis, treatment and management.
        Emerg Med Clin North Am. 2004; 22: 2423-2443
        • Bush S.P.
        Snake suction devices don't remove venom: they just suck.
        Ann Emerg Med. 2004; 43: 2187-2188
      1. 2005 American Heart Association guidelines for cardiopulmonary resuscitationemergency cardiovascular care.
        Circulation. 2005; 112: 196-203
        • Ni Riordain R.
        • McCreary C.
        Head and neck cancer information on the Internet: Type, accuracy and content.
        Oral Oncol. 2009; 45: 675-677
        • Thompson A.E.
        • Graydon S.L.
        Patient-oriented methotrexate information sites on the Internet: a review of completeness, accuracy, format, reliability, credibility, and readability.
        J Rheumatol. 2009; 36: 41-49
        • Marriott J.V.
        • Stec P.
        • El-Toukhy T.
        • et al.
        Infertility information on the World Wide Web: a cross-sectional survey of quality of infertility information on the Internet in the UK.
        Hum Reprod. 2008; 23: 1520-1525
        • Wilson P.
        How to find the good and avoid the bad or ugly: a short guide to tools for rating quality of health information on the Internet.
        BMJ. 2002; 324: 598-602
        • Sigouin C.
        • Jadad A.
        Awareness of sources of peer-reviewed research evidence on the Internet.
        JAMA. 2002; 287: 2867-2869
        • Kunkel D.
        Bites of venomous reptiles.
        Emerg Med Clin North Am. 1984; 2: 563
        • Stahnke H.
        The L-C treatment of venomous bites or stings.
        Am J Trop Med Hyg. 1953; 2: 142-143
        • Stahnke H.
        • Allen F.
        • Horan R.
        • et al.
        The treatment of snake bite.
        Am J Trop Med. 1957; 6: 323-335
        • Cohen W.
        • Wetzel W.
        • Kadish A.
        Local heat and cold application after eastern cottonmouth moccasin (Agkistrodon piscivorus) envenomation in the rat: effect on tissue injury.
        Toxicon. 1992; 30: 1383-1386
        • Ya P.M.
        • Perry Jr, J.F.
        Experimental evaluation of methods for the early treatment of snake bite.
        Surgery. 1960; 47: 975-981
        • Guderian R.
        • Mackenzie C.
        • Williams J.
        High voltage shock treatment for snake bite (letter).
        Lancet. 1986; 2: 229
        • Howe N.R.
        Electric shock does not save snakebitten rats.
        Ann Emerg Med. 1988; 17: 254-256
        • Johnson E.K.
        • Kardong K.V.
        • Mackessy S.P.
        Electric shocks are ineffective in treatment of lethal effects of rattlesnake envenomation in mice.
        Toxicon. 1987; 25: 1347-1349
        • Snyder C.
        • Murdock R.
        • White G.
        • et al.
        Electric shock treatment for snakebite (letter).
        Lancet. 1989; 1: 1022
        • Stoud C.
        • Amon H.
        • Wagnor T.
        • Falk J.L.
        Effect of electric shock therapy on local tissue reaction to poisonous snake venom injection in rabbits.
        Ann Emerg Med. 1989; 18: 447
        • Dart R.
        • Gustafson R.
        Failure of electric shock treatment for rattlesnake envenomation.
        Ann Emerg Med. 1991; 20: 659-661
        • Russell F.
        A letter on electroshock for snakebite.
        Vet Hum Toxicol. 1987; 29: 320
        • Alberts M.B.
        • Shalit M.
        • LoGalbo F.
        Suction for venomous snakebite; a study of “mock venom” extraction in a human model.
        Ann Emerg Med. 2004; 43: 181-186
        • Meric F.
        • Bernstam E.
        • Mirza N.
        • et al.
        Breast cancer on the World Wide Web: cross sectional survey of quality of information and popularity of websites.
        BMJ. 2002; 324: 577-581
        • Smalligan R.D.
        • Campbell E.O.
        • Ismaill H.M.
        Patient experiences with MedlinePlus.gov: a survey of internal medicine patients.
        J Investig Med. 2008; 56: 1019-1022